Summary: Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) involves the reactivation of endogenous pluripotency genes and global DNA demethylation, but temporal resolution of these events using existing markers is limited.Here, we generate murine transgenic lines harboring reporters for the 5-methylcytosine dioxygenase Tet1 an

Abstract The quest for different natural compounds for different biomedical applications especially in the treatment of cancer is at a high pace with increasing incidence of severity.d-limonene has been portrayed as one of the effective potential candidate centered to the context of breast cancer.The anticipation of its count as an effective biomed

The Kalman filter is an iterative state estimation algorithm employed extensively, including in electricity generation, aerospace, robotics, etc.Inputting noisy measurements on a dynamical system, it outputs a state estimate and associated covariance.This work focuses on the time evolution of the covariance matrix given regular, uniform measurement

The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria.Here, we review recent structural and functional data on MacB and Whisks its homologs.MacB has a fold that is distinct from other structurally character

Several have challenged the idea that the act of educating is a neutral endeavour.Following this line of thought, this article intends to examine a common concept often taken for granted: curiosity.The aim of this article is to explore the notion of curiosity in an early-childhood-education-and-care (ECEC) context in Norway in order to provide new